adaptor molecule造句

• Adaptor molecules are responsible for self-assembly and recruitment.
• STAMBP has been shown to interact with RNF11, Signal transducing adaptor molecule and GRAP2.
• The molecule was determined to be an IRS-1 adaptor molecule involved the insulin response cascade.
• Cytokine-mediated signal transduction in the JAK-STAT cascade requires the involvement of adaptor molecules.
• The CAP1 are CAP2 proteins are also known as FADD / MORT1, an adaptor molecule with a death domain.
• One such signal-transducing adaptor molecule contains an SH3 domain that is required for induction of MYC and cell growth.
• The adaptor molecules were eventually shown to be tRNAs and the catalytic " ribonucleic-protein complexes " became known as ribosomes.
• As a consequence RIP1 forms a cytosolic complex with the adaptor molecule FADD and caspase 8, which leads to cell death.
• These proteins are known as MyD88, Tirap ( also called Mal ), Trif, and Tram ( TRIF-related adaptor molecule ).
• This domain structure and the tyrosine and serine-rich content of the protein product is typical of an " adaptor molecule " used in cell signalling pathways.
• The attachment of fibronectin to the extracellular domain initiates intracellular signalling pathways as well as association with the cellular cytoskeleton via a set of adaptor molecules such as actin.
• This allows the adaptor molecule " Fas-associated death domain " ( FADD ) to bind the death domain of Fas through its own death domain.
• The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A / TNFR1 and mediates programmed cell death signaling and NF-kappaB activation.
• Upon ensuing death domain ( DD ) aggregation, the receptor complex is internalized via the cellular adaptor molecule FADD to bind the death domain of Fas through its own death domain.
• Integrins lack kinase activity; hence, integrin-mediated signal transduction is achieved through a variety of intracellular protein kinases and adaptor molecules, the main coordinator being integrin-linked kinase.
• BCAR1 is a ubiquitously expressed adaptor molecule originally identified as the major substrate of v-Src and Cas family of adaptor proteins and can act as a docking protein for several signalling partners.
• Crick proposed that there was a corresponding set of small " adaptor molecules " that would hydrogen bond to short sequences of a nucleic acid, and also link to one of the amino acids.
• The protein encoded by this gene binds to the SH3 domain of the signal-transducing adaptor molecule, and plays a critical role in cytokine-mediated signaling for MYC induction and cell cycle progression.
• This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors.
• When the TCR engages with antigenic peptide and MHC ( peptide / MHC ), the T lymphocyte is activated through signal transduction, that is, a series of biochemical events mediated by associated enzymes, co-receptors, specialized adaptor molecules, and activated or released transcription factors.